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Unravelling the causes of poor growth in piglets: analysis of the impact of perinatal events, nutrient flow and the gut-brain axis on metabolic response and feeding behaviour

Principal Investigators (IPs): Susana María Martín Orúe and Jose Francisco Pérez Hernández.

Poor-performing piglets are particularly relevant to the swine industry, as they represent one of the main sources of batch variability and one of the major concerns for producers. Growth variability has negative economic consequences, as it leads to carcass depreciation and prolonged occupancy of facilities.

Previous studies conducted by our research groups have shown that one of the main reasons for this variability lies in the difficulties experienced by some piglets in adapting to dry feed after weaning. Numerous factors may contribute to this variable response, and despite significant advances, there is still a lack of knowledge regarding the underlying causes.

This joint project between UAB and IRTA aims to address this challenge by exploring the main factors limiting piglet performance and by evaluating new nutritional strategies based on the development of enrichment feeds and management practices that help minimise the problem.

Initially, we will seek to identify the main biological determinants of poor performance in piglets by considering different perinatal events as well as various blood biomarkers. In addition, as a proof of concept, we will investigate the impact of early nutrient flow on piglet metabolism and lean growth.

The role of the early-life microbiota will be assessed using an in vitro piglet colon model, analysing the potential of different nutritional and biotic strategies to modulate the microbiota, with possible effects on the gut-brain axis.

At the same time, several trials will be conducted to develop enrichment feeds for piglets by combining different innovative manufacturing technologies. These feeds will be assessed through preference tests, with the aim of selecting those showing the highest acceptance for use within a sensory variety strategy during the suckling period (creep feed) and throughout the weaning period.

Finally, management strategies based on intermittent suckling will also be evaluated, exploring the role of appetite regulation mechanisms and feeding behaviour.

In summary, this project aims to improve our understanding of the underlying causes of poor performance in some piglets and to provide innovative nutritional and management strategies that address the current needs of the swine industry.


Proyecto PID2023-146722OB-C21 financiado por: